I am a Computational Biologist working in immunogenomics with Dr. Soumya Raychaudhuri in collaboration with Dr. Michael Brenner at Harvard Medical School, Brigham and Women’s Hospital (BWH), and Broad Institute of Harvard and MIT (2017 - Present). My research interests lie in the development and application of computational methods and pipelines to decipher pathogenic cell states and disease-associated features for autoimmune diseases using high-dimensional single-cell multi-omics data. I have been collaborating with Dr. Laura Donlin on pathologic mechanisms of macrophages in autoimmune diseased tissues. I am also part of the BWH 10X Single Cell Genomics Core, where I provide consulting on bioinformatics protocols to academic customers such as immunology, rheumatology, pulmonology, and pathology labs.
During my PhD (2013 - 2017), I worked with Dr. Patrick Flaherty on Bayesian statistical modeling and machine learning for large-scale NGS-seq data to characterize patient heterogeneity in clinical samples. I also worked with Dr. Andrew C. Trapp on developing global optimization algorithms to solve variations of mixed membership models.
Research Scientist in Immunogenomics, 2021
Harvard Medical School and Broad Institute, MA USA
PhD in Bioinformatics and Biomedical Engineering, 2017
Worcester Polytechnic Institute, MA USA
Research Associate, 2013
Chinese Academy of Sciences
BS and MS in Computer Science/Bioinformatics, 2012
Jilin University, China
Autoimmune, cytokine, macrophage, single-cell integration, COVID-19
Invited and oral talks
Updated by 2020-08-20
If you’d like to learn more about my work, you can find my CV here.
Code, data, and PDF for each paper are provided. Ask me for questions.